Website Wageningen University and Research
Always wanted to know why plants are resistant to almost all and thus a nonhost for most diseases? Then now there is a challenging project in which you can explore a rare susceptible variant of a nonhost species to discover its underlying gene and mechanism of resistance. Do you want to contribute to improving our knowledge of immunity from a crop-wild relative of lettuce? Please read on, and apply!
Function RequirementsWorking conditions
|We are looking for an enthusiastic and highly motivated PhD student to work on resistance against downy mildew in the wild lettuce species, Lactuca saligna.
You will be resolving the genetics of a rare susceptible phenotype in a nonhost species. Downy mildew is a notorious disease for the crop lettuce, Lactuca sativa. The crop-wild relative, Lactuca saligna, is completely resistant to downy mildew and considered a nonhost species. L. saligna and L. sativa have a fascinating evolutionary relationship, as they diverged about 3 Million years ago, but can still be crossed. Previous interspecific mapping attempts (cross L. saligna x L. sativa) for complete resistance were hindered partly by reproductive barriers and showed a complex inheritance of the resistance. A different opportunity to explore immunity in the species L. saligna presents itself in the exceptional existence of a rare susceptible variant. We like to explore this rare variant and answer the following questions: What gene and mechanism causes this susceptibility ? How can we use this information to identify or design a gene variant(s) resulting in resistance in the crop lettuce?
About the LettuceKnow research program
LettuceKnow (a NWO-TTW perspective program) started in 2019 to investigate key resilience and architecture traits of lettuce. Lettuce is an important component of a healthy diet with an extensive global use. The project aims to identify molecular mechanisms and genes for resilience and architecture. The basis for this is the combination of large-scale transcriptomics of a diversity panels of 500 wild and cultivated Lactuca accessions, cutting-edge phenotyping, powerful integrative bioinformatics & machine learning, and state-of-the-art plant biology. The LettuceKnow team brings together leading scientists in the areas of plant biology, genomics and data sciences to enable the optimal use of big data and discover the genes/alleles underlying important traits. It comprises a diverse research community with a strong focus on resolving major challenges for Dutch lettuce breeders to develop resilient and sustainable varieties that are adapted to changing climate conditions.
|Wageningen University & Research offers excellent terms of employment. A few highlights from our Collective Labour Agreement include:
• sabbatical leave, study leave, and paid parental leave;
• working hours that can be discussed and arranged so that they allow for the best possible work-life balance;
• the option to accrue additional flexible hours by working more, up to 40 hours per week;
• there is a strong focus on vitality and you can make use of the sports facilities available on campus for a small fee;
• a fixed December bonus of 8.3%;
• excellent pension scheme.In addition to these first-rate employee benefits, you will receive a fully funded PhD position and you will be offered a course program tailored to your needs and the research team.
In principle this is a PhD position starting between Oct 1 and Dec 1, or at the earliest convenience. We offer you a temporary contract for 12 months which will be extended with three years if you perform well (after go/no go evaluation). Salary will increase from € 2395,- gross per month in the first year up to € 3061,- in the last year, based on a full-time appointment (38 hours per week). (A contract for 0.8 FTE can be discussed.)
The PhD student will also participate in the graduate school Experimental Plant Sciences of WUR, which offers opportunities for courses supporting scientific as well as personal and professional development
You are going to work at the greenest and most innovative campus in Holland, and at a university that has been chosen as the “Best University” in the Netherlands for the 16th consecutive time.
To apply for this job please visit www.connexys.nl.